Preclinical Research Capabilities
Obesity - Metabolic syndrome
DESCRIPTION:
At Albor Biotech, we specialize in preclinical research focused on obesity, insulin resistance and diabetes. We combine validated animal models with comprehensive metabolic phenotyping to evaluate drug efficacy, characterize metabolic responses and investigate the mechanisms underlying disease and treatment effects.
Our capabilities include assessment of glucose and lipid metabolism, energy expenditure, food intake, body composition and tissue-specific metabolic function, together with biochemical, molecular and tissue-level analyses.
Diabetes - Insulin resistance
Preclinical services for insulin resistance and type 2 diabetes using advanced models.
DESCRIPTION:
Albor Biotech offers preclinical CRO services using innovative and benchmarked animal models of obesity, insulin resistance and type 2 diabetes to study the effects of potential new therapies.
Our clients benefit from our experts’ capabilities, which include classical in vivo test experiments (GTT, ITT, tissue-specific insulin sensitivity, GSIS, etc.) and our gold standard tracer- based experiments: euglycemic – hyperglycemic – hyperinsulinemic clamp with 3H-glucose (for glucose turnover, hepatic glucose production, etc.) and 14C-2-deoxyglucose (for glucose tissue uptake in insulin-sensitive organs).
Metabolic Liver Disease & Hepatic Fibrosis
DESCRIPTION:
Albor Biotech provides specialized preclinical services for the study of metabolic liver disease, steatosis and hepatic fibrosis. Our expertise combines validated dietary and chemical models with comprehensive metabolic, biochemical and histological characterization.
Studies can evaluate liver function, fibrosis progression, inflammation, steatosis and treatment response through biochemical biomarkers, gene expression, histopathology and tissue-specific molecular analysis.
Oncology
DESCRIPTION:
Albor Biotech provides preclinical oncology research services combining in vitro assays with relevant in vivo tumor models to characterize therapeutic efficacy and treatment response.
Our capabilities include subcutaneous, orthotopic and metastatic models, together with tumor growth monitoring, survival assessment and advanced tissue and molecular characterization. Histopathology, immunohistochemistry, immunofluorescence, biomarkers and immune profiling can be integrated to investigate treatment mechanisms and support translational decisions.
NeuroBehavior
DESCRIPTION:
We provide preclinical behavioral and functional assessment to characterize the effects of therapeutic candidates on cognition, memory, motor function, exploratory activity and stress-related behavior.
Flexible behavioral batteries can be designed according to the therapeutic area, mechanism of action and study objectives, integrating complementary endpoints to provide a comprehensive assessment of functional outcomes.
Nutraceutics & Novel Foods
DESCRIPTION:
At Albor Biotech, we provide tailored preclinical research services for nutraceuticals, functional ingredients and novel food products, generating scientific evidence to support product development and biological efficacy.
Our studies combine in vitro and in vivo approaches to investigate metabolic health, inflammation, oxidative stress, mitochondrial function and other relevant biological effects. Depending on the product and development objectives, we can integrate functional assays, bioenergetics, metabolic phenotyping, biomarkers, molecular analysis and tissue characterization.
Our flexible approach allows study designs to be adapted to the specific ingredient, product and intended biological effect, providing mechanistic and efficacy data to support further development.
Animal health
Preclinical services for animal health, evaluating pharmacological treatments and nutrition effects on metabolism and well-being.
DESCRIPTION:
Our CRO service specialized in animal nutrition is designed to elucidate the effectiveness of pharmacological treatments on the health of both domestic and farming animals, evaluating the effect they have on the control of body weight, appetite, and carbohydrate and lipid metabolism. The effect of different animal feeds or foods in development phase on the metabolism and general well-being of the animal is also evaluated.
Consultancy
DESCRIPTION:
Alongside our preclinical CRO services, we provide tailored scientific consulting to support the specific needs of each client. Our experienced scientific team draws on extensive expertise in preclinical research and drug development to help clients design efficient, scientifically robust and cost-effective studies.
From experimental design and model selection to study execution and data interpretation, we work closely with our clients to identify the most appropriate strategies, optimize study design and generate decision-ready data to support the progression of their candidates.
